Ovarian Neoplasm: Diagnostic Accuracy of Ultrasound Guided Fine Needle Aspiration Cytology with Histopathological Correlation

Background: Ovarian lesions are one of the most frequent lesions in women .The pre-operative diagnosis relies mainly on clinical and radiological findings while post-operative diagnosis is made by histo-pathological examination. With the advent of accurate imaging techniques like USG and CT scan, guided FNAC can prove to be an efficient diagnostic modality for ovarian neoplasm. Aims & Objectives: To evaluate the utility and accuracy of cytological diagnosis in ovarian lesions either nonneoplastic or neoplastic. Material and Methods: A retrospective study was carried out over a period of 3.5 years. Total 125 cases were reported in cytology during this period. Diagnosis was established by FNAC performed under image guidance and confirmed by Histo-pathological examination. Cytology smears were stained by Pap and H&E stain. Histology slides were stained with H&E stain. Result: Of the total 125 cases, cytological diagnosis was offered in 110 cases of which 17 were non-neoplastic, 50 benign and 43 malignant. Cytological correlation with histopathological specimens was possible in 69 cases only. Concordant diagnosis was achieved in 63 cases while 6 were discordant. Sensitivity and specificity of cytological diagnosis were 77.2% and 97.9% respectively. Conclusion: Guided FNAC for ovarian lesions is a relatively quick, easy and patient friendly procedure with fair diagnostic accuracy and minimal patient mortality. Cytological diagnosis can be used as a preoperative diagnosis for management of patient. Histopathology remains the gold standard procedure.